Description
What Are Aspadol 100mg Tablets?
Aspadol 100 mg is a prescription-strength analgesic formulated to manage moderate to severe acute and chronic pain. Its active ingredient, Tapentadol, is a centrally acting synthetic opioid that combines μ-opioid receptor agonism with norepinephrine reuptake inhibition, offering dual-action pain relief.
Aspadol 100mg Tablets Summary
| Type Of Medication | Opioid Pain Medication |
| Active ingredient | Tapentadol Hydrochloride |
| Effective within | 30 minutes |
| Manufacturer | Signature Pharmaceuticals & Research Ltd. |
| Brand Drug | Yes |
Composition and Mechanism of Action
Active Ingredient: Tapentadol Hydrochloride 100 mg
Form: Immediate-Release (IR) Oral Tablet
Tapentadol operates through two primary mechanisms:
μ-Opioid Receptor Agonism: It binds to opioid receptors in the brain and spinal cord, altering the perception of pain.
Norepinephrine Reuptake Inhibition (NRI): By inhibiting the reuptake of norepinephrine, it enhances the body’s natural pain suppression pathways.
This dual mechanism provides effective analgesia with a potentially lower incidence of gastrointestinal side effects compared to traditional opioids.
Indications
Aspadol 100 mg is indicated for the relief of moderate to severe pain, including:
Postoperative pain
Musculoskeletal pain
Neuropathic pain
Pain associated with cancer
It is particularly beneficial for patients who require continuous, around-the-clock opioid treatment and for whom alternative treatment options are inadequate.
How To Take Aspadol 100mg Tablet?
- Swallow the tablet whole with a glass of water.
- Do not break, cut, or chew the medicine before intake.
- It can be taken with or without food. However, people with nausea should take it after a meal.
Side Effects
Common Side Effects:
Nausea and vomiting
Dizziness and drowsiness
Constipation
Headache
Dry mouth
Fatigue
Serious Side Effects:
Respiratory depression
Seizures
Severe allergic reactions (e.g., rash, itching, swelling)
Confusion or hallucinations
Low blood pressure
Warnings and Precautions
Dependency and Abuse: Tapentadol has a potential for abuse and dependence. Use the lowest effective dose for the shortest duration necessary.
Respiratory Depression: Monitor for signs, especially in patients with respiratory disorders.
Interactions: Avoid concurrent use with alcohol, other opioids, or central nervous system depressants.
Pregnancy and Lactation: Use only if the potential benefit justifies the potential risk to the fetus or infant.
Elderly Patients: Use with caution; they may be more sensitive to adverse effects.
Storage And Disposal
- The Aspadol 100 mg tablets should be stored in a cool, dry place.
- Keep the medication out of reach of pets and children.
- Disposal of expired and unwanted medications should be done by following a medicine take-back program.
